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Comparison of long-pulsed alexandrite laser and topical tretinoin-ammonium lactate in axillary acanthosis nigricans: A case series of patients in a before-after trial

Managing GLP-1 Side Effects: Our Top Tips for Success GLP-1 agonists, like semaglutide and tirzepatide, are groundbreaking treatments for managing type 2 diabetes and obesity

Seek urgent medical attention (call 999 or go to A&E) if you experience: Severe or persistent vomiting, or inability to keep fluids down for more than 24 hours Severe upper abdominal pain, particularly if it radiates to the back (possible pancreatitis) Severe right-sided upper abdominal pain, with or without fever or yellowing of the skin or eyes (possible gallbladder problems a recognised class signal with GLP-1 receptor agonists) [14] [15] Contact NHS 111 or your GP if you experience: Fast, irregular heartbeat or palpitations Symptoms of hypoglycaemia (shakiness, sweating, confusion), particularly if taking insulin or other glucose-lowering medicines Dizziness or signs of dehydration (reduced urine output, dry mouth, light-headedness) If you think you have experienced a side effect from any medicine, you can report it via the MHRA Yellow Card Scheme at yellowcard.mhra.gov.uk or through the Yellow Card app

In essence, GLP-1 appears to modulate the DMN, pushing it in the direction of balance

Common side effects such as nausea and early satiety often diminish with time, but proactive counseling can improve tolerance