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At week 52, the total daily insulin dose was decreased from baseline with oral semaglutide 14 mg for patients on basal, premixed and basal-bolus insulin, and were generally consistent regardless of background insulin regimen (see Fig

In studies on GLP-1 medications, people who lost more than an average of 15% of their weight were more likely to notice increased hair loss

For researchers currently building protocols based on Phase 2 data, the Phase 3 dose selection validates the 4mg to 12mg range as the therapeutic window

PLOS ONE 12 , e0169781 (2017)
These are not voluntary guidelines
