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[DOI] [PMC free article] [PubMed] [Google Scholar] 32.Lean M.E., Carraro R., Finer N., Hartvig H., Lindegaard M.L., Rssner S., et al

BREAKING: Semaglutide for MASH: A Step Forward in Metabolic Liver Disease Phase 3 data just released (NEJM 2025): In 800 patients with biopsy-confirmed MASH and fibrosis stage 23, semaglutide 2.4 mg weekly delivered impressive results at 72 weeks (compared to placebo): Histologic Outcomes: 63% achieved resolution of steatohepatitis without worsening fibrosis (vs

Avinash Ketwaroo, gastroenterologist and associate professor of medicine at Yale School of Medicine, recommends against the BRAT diet instead prescribes these diets for some common conditions: Low-lactose diet for bloating and gas due to lactose intolerance Low FODMAP diet for irritable bowel syndrome High-fiber diets for diverticulosis For patients with acid reflux, he recommends avoiding or minimizing spicy foods, caffeine, alcohol and chocolates

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Insufficient Dosage and Titration Timing One of the most common reasons semaglutide underperforms is that patients haven't reached a therapeutic dose yet