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The medication may worsen diabetic retinopathy in patients who already have this condition
This finding suggests that the primary mechanism of GLP-1RAs in the retina is likely direct neuroprotection
GLP-1RAs can cross the bloodbrain barrier and activate brain GLP-1 receptors, leading to neuroprotection by improving insulin signaling, reducing tau hyperphosphorylation, and enhancing cognitive function in diabetic and aging models
AMPK, metabolism, and vascular function
Normality of the distribution was evaluated using Shapiro-Wilk test and as several variables were not normally distributed, non-parametric tests were used for statistical analyses
