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There are also some bigger risks, including adverse effects such as pancreatitis and problems with how the kidneys work

In the series of 11 clinical trials (SUSTAIN programme) GLP-1 agonists demonstrated improved glycemic control in patients with diabetes (as measured by HbA1c) but also showed a consistent weight loss in trial participants

On average, individuals taking Ozempic can expect to lose around 5-10% of their initial body weight

4.3 GLP-1 RAs in patients with DM2 Several randomized clinical trials have demonstrated the cardiovascular benefits of GLP-1 RAs in patients with T2DM

placebo based on their pre-existing level of DR