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According to results from a multinational survey interviewing 3742 diabetic patients, an oral antidiabetic drug is preferable as the first choice of medication and medications for long-term use, especially for those with high HbA1c and comorbidities (obesity, hypertension, dyslipidaemia) [96]

Until robust pregnancy data emerges, both medications fall under the same precautionary guidance

Transcriptomic analyses were generated from publicly-accessible data (NCBI GEO databases: GSE160938, GSE166649, GSE228192)

However, studies have shown that a reduction in muscle mass accompanies total weight loss

If additional glycaemic control is needed after at least 4 weeks, the dose may be increased to 1 mg once weekly and potentially to 2 mg once weekly if required and tolerated