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Thus, direct activation of GLP1 receptors via GLP1-RAs may be requisite to leverage this system as a potential therapeutic to reduce alcohol intake

However, the medication's bioavailability is relatively low (approximately 1%), which is why Rybelsus tablets contain the absorption enhancer salcaprozate sodium (SNAC)

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Serious but rare risks include pancreatitis, gallbladder events, and a thyroid C-cell tumor boxed warning from rodent studies
