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When you lose fluids through GI side effects, you also lose electrolytes

Endocrine regulation of central GLP-1 secretion As discussed above, in addition to enteroendocrine L-cells, GLP-1 is also produced in a discrete set of non-TH-positive neurons in the caudal portions of the NTS [86,148,[346], [347], [348]], and these hindbrain GCG + positive neurons are the primary source of endogenous brain GLP-1 [90]

Arylalkylamine-containing foods, such as bananas, beer, cheese, mayonnaise, nuts, onions, raisins, sour cream, wine and yogurt, have also shown to increase symptoms of a possible bladder infection

And in 5-7 years, they may well vanish when the GLP1 Gene-Therapy comes in

Stopping therapy is often followed by weight regain