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Clinical Evidence: Retatrutide's Impressive Results In a recent phase 2 trial for obesity, retatrutide demonstrated remarkable efficacy: Up to 24.2% weight loss at 48 weeks with the highest dose, surpassing the weight loss seen with both semaglutide(15-17%)and tirzepatide (22.5%) at their respective highest doses

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Coverage gaps, steep out-of-pocket costs, and payer-imposed roadblocks stall progress before treatment even begins, while stigma, fragmented care, and shifting patient perceptions chip away at long-term adherence

RESULTS: Diet-induced thermogenesis (DIT) was lower (47%) on the GLP-1 infusion than on the saline infusion (P<0.0001)