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In the closing three months of the year, US healthcare providers wrote more than nine million prescriptions for Ozempic, Wegovy, and other GLP-1 drugs, with Novos Ozempic making up more than 65% of total prescriptions primarily off-label for weight loss purposes

Study participants reported a median body mass index (BMI) of 35.1 kg m 2 before initiating GLP1 treatment, with 96.8% of participants having a BMI of at least 25 at baseline

Priya Jaisinghani , an endocrinologist and obesity medicine specialist at NYU Langone Health, discussed the effectiveness of the two formulations during an Endocrine Society webinar about GLP-1 pills in December 2025

Results vary among individuals and are not guaranteed