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Description
However, in murine models, exendin-4 demonstrates about 5,500-fold greater potency in improving glucose control, evidenced by the percentage fall in plasma glucose at 1 hour (87)
Higher GLP-1 levels inversely correlate with binge-like eating in animals 210,211 , and binging behavior is associated with lower GLP-1R in the nucleus of the solitary tract 212
This is an injection into a vein thats given over time
Concerns exist about potential risks such as pancreatitis or pancreatic cancer, and long-term cardiovascular effects
At 20 mg/mL, that same 10 mg dose requires only 25 units (0.25 mL)
