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For instance, leptin suppresses the activity of AMP-activated protein kinase (AMPK) in POMC neurons, which is permissive for their firing and subsequent peptide production [7]
Semaglutide and tirzepatide are only approved for the treatment of a certain number of conditions: obesity and overweight, type 2 diabetes, sleep apnea, and cardiovascular disease
doi: 10.1056/NEJMoa1600869 Drucker DJ

10.1080/17474124.2023.2172397 22 GuoT.YanW.CuiX.LiuN.WeiX.SunY.et al (2023)