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Its important to remember that the benefits of B-12 injections may vary depending on individual circumstances and existing B-12 levels
Proc Natl Acad Sci USA 104:1506915074 [DOI] [PMC free article] [PubMed] [Google Scholar] Shin YK, Martin B, Golden E, Dotson CD, Maudsley S, Kim W, Jang HJ, Mattson MP, Drucker DJ, Egan JM, Munger SD 2008 Modulation of taste sensitivity by GLP-1 signaling

Mild nausea, reduced appetite, feeling full quickly, and some fatigue are all normal first-week symptoms that don't require immediate medical attention
Newer JAK inhibitors (tofacitinib, upadacitinib) and S1P modulators (ozanimod) offer additional options
