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Another limitation of GLP-1 RAs is that discontinuation commonly leads to substantial body weight regain, and many patients who regain weight subsequently restart GLP-1 RA therapy, resulting in a recurrent cycle of body weight loss and gain [10]

That said, compounded medications are not equivalent to FDA-approved drugs in terms of the regulatory review they have undergone
Zheng, H., Ryzhov, I

Physiol Behav 2024;281:114565

Your appetite will gradually come back over a few weeks to months after you stop
