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Moreover, in 5xFAD mice, exenatide reduces A deposition, the expression of NLRP2 inflammasome in astrocytes, and TNF- and IL-1 expression in the piriform cortex [160]

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About the author Rekha Kumar, MD, MS, is the head of medical affairs at Found

Recent studies have suggested that novel weight-loss drugs targeting glucagon-like peptide-1 (GLP-1) may also improve HFpEF symptoms, but their effect on important outcomes like hospitalization and death has not been evaluated in large populations
