tirzepatide risk of cancer GLP-1s appear to cut risk. Researchers are asking why and how : NPR Weight-loss jabs 'slash cancer risk
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The hormone Glucagon has the opposite effect it tells the body to release glucose into the blood to raise sugar levels

The latter hypothesis derives from observations that GIP modulates vascular tone across peripheral vascular beds by enhancing endothelial nitric-oxide synthesis through eNOS activationan effect abolished by CaMKK, PLC, or AMPK inhibitionand demonstrates anti-inflammatory actions in adipose tissue and endothelium that correlate with increased cAMP signaling in select vascular beds, though a direct cAMP-dependent mechanism underlying its anti-inflammatory effect has yet to be conclusively established 49

2021 Mar 30;30(1):32-43

Brain Sci 14:617 Badulescu S, Tabassum A, Le GH et al (2024) Glucagon-like peptide 1 agonist and effects on reward behaviour: a systematic review

Evening injection (8 to 10 PM) allows you to sleep through the initial peak