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Additional factors such as increased release of adiponectin from adipose tissue, amelioration of insulin resistance in liver and peripheral tissues, and improved circulatory lipid profile all contribute to the reduced risk of ASCVD (267)

But, from the data we have so far, it seems that they will be similar to those of Wegovy and Mounjaro

For Novo Nordisk, the decision further cements its dominance in the GLP-1 space and intensifies competition as rivals race to develop oral alternatives

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This was likely driven by the desire to avoid a potential messy lawsuit from Novo and increased federal scrutiny of its compounded GLP-1 business