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Suicidal Behavior : Semaglutide may impact mental health, particularly in individuals with depression or a history of suicidal thoughts

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A new preclinical study at Northwestern Universitys Feinberg School of Medicine found that disrupting complex I function in mouse dopaminergic neurons led to progressive PD-related motor deficits, with loss of dopamine release in the substantia nigra being critical for motor deficits (40)

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But when they are dosed for weight loss, weight loss IS just a side effect of the drug