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1d) demonstrated a distinct response pattern

Reduced calorie and carbohydrate intake

Nonetheless, for new GLP-1 drugs in development, it is imperative to evaluate potential drug interactions since this drug class can alter the efficacy of concomitant medications or increase the risk of adverse events as a result of higher exposure to a co-administrated drug

Saffron extract, chromium picolinate, and specific probiotic strains like Akkermansia muciniphila have also shown activity in pathways linked to glucagon-like peptide production

As daily injections are a barrier for some patients with T2D, there was focus on improving convenience, ideally with an effective GLP-1 analog that could be administered once weekly