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Combined therapy with two classes of antidiabetic agents, namely, dipeptidyl peptidase 4 inhibitors and sodium-glucose co-transporter-2 inhibitors, target several pathophysiological pathways

A team of researchers from the University of Iowa has unveiled concerns about the use of semaglutide, a widely prescribed GLP-1 receptor agonist for type 2 diabetes and obesity, in patients with neuroendocrine neoplasms (NENs)

In a study published in NEJM SURMOUNT 5*, an international comparative open-label, controlled trial, adult participants with obesity but without type 2 diabetes the 2 agents were compared in maximally tolerated recommended doses

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