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A consistent pattern emerges in phenotypes with a high metabolic burden, such as obesity and IGT or pre-diabetes, improvements in fasting glucose, OGTT curves, and HbA1c are more pronounced, with some subjects even reverting from IGT to normoglycemia

GLP1 receptor agonists-effects beyond obesity and diabetes

Meta-analysis of 35 clinical trials demonstrated a modest reduction in LDL cholesterol, total cholesterol, and triglycerides in patients treated with GLP-1 RAs compared to controls (58)

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