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J Bone Miner Res 2008
The hippocampus, a brain structure associated with memory formation, seems to be particularly affected in depression [43, 44]

2025;8(4):e252964

In a pilot trial evaluating 104 amnestic MCI and early-stage AD patients, 20 IU and 40 IU doses of intranasal insulin improved Alzheimers Disease Assessment Scale-Cognitive subscale (ADAS-Cog 12) scores compared to placebo-treated patients, with improvements in delayed recall observed 2 months following cessation of treatment in the 20 IU group

doi: 10.1152/ajprenal.00064.2012