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1.2 Current challenges in diabetes and obesity management Obesity and diabetes are becoming increasingly common worldwide, presenting serious challenges for public health that cannot be ignored

In other words, you can start reaching your goals without the hassle of fitting in a doctors appointment or making it to the pharmacy before it closes

doi: 10.1002/ddr.21643 [DOI] [PMC free article] [PubMed] [Google Scholar] 62

Recent evidence suggests that GLP-1RAs may exert direct renoprotective effects independent of their metabolic benefits

This indicates that metformin promotes GLP-1 release through a non-vagal M3 muscarinic pathway (Mulherin et al., 2011)