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Glucagon-like peptide-1 receptor agonists (GLP-1RAs), which are widely used for the treatment of T2DM and promote weight loss in individuals with obesity, have demonstrated significant cardiovascular benefits

Diarrhea during semaglutide treatment is a pharmacological response, not a failure indicator

Retatrutide Titration Schedule: Standard Phase 2 Protocol The table below reflects the Phase 2 trial protocol for the primary escalation arm (Jastreboff et al., NEJM 2023)

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