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The 7.2 mg dose was approved to help patients achieve deeper weight reductionproducing nearly 20% total weight loss in the STEP UP clinical trialsputting its efficacy much closer to that of tirzepatide

This stratified approach avoids the one-size-fits-all assumptions that have constrained past indication extension attempts and provides a clearer, evidence-led path to expanding GLP-1 use where it is biologically and clinically justified.

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External Review : If the internal appeal is unsuccessful, you may have the option for an external review where an independent third party evaluates the decision