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Major GI, gallbladder, pancreatic or glucose related risk

The 52-week ELEVATE UC 52 study showed 27% clinical remission in patients taking Velsipity versus 7.4% in those who were part of the placebo group at week 12, and 32.1% clinical remission compared with 6.7% at week 52

These effects are greater than those seen with older weight loss medications (typically ~5% total weight loss) and close to typical weight loss seen with bariatric surgery

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HA accelerates the conversion of P to androstenedione and T in PCOS, thereby increasing circulating serum T