glp 1 versus glp 2 GLP-1 and GLP-2 Orchestrate Intestine Integrity, Gut Microbiota, and Immune System Crosstalk GLP-1 and GLP-2 Orchestrate Intestine

And at what point should we all be on it?

This study included 41 participants (RYGB: n=21, OAGB: n=20) from the randomized RYSA trial with similar amounts of bypassed intestine between the procedures

without HF: HR 0.44

Multiple randomized controlled trials and meta-analyses in patients with type 2 diabetes and obesity demonstrate that GLP-1RA therapy either preserves or modestly increases bone mineral density (BMD) at key skeletal sites lumbar spine and hip, GLP-1RAs also favorably modulate bone turnover markers, increasing bone formation markers (P1NP, osteocalcin, bone-specific alkaline phosphatase) and reducing bone resorption markers (-CTX), suggesting a net positive or neutral effect on bone remodeling

Safety isnt optional