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Liraglutide, a glucagon-like peptide 1 receptor agonist, exerts analgesic, anti-inflammatory and anti-degradative actions in osteoarthritis

Multiple factors will make more people engage and stick to using the drugs: Pills : as many users are repelled by the need to inject themselves regularly, the emergence of a pill alternative could boost sales and retention

At the same time, the data imply that a medicinal chemistry campaign focusing on engineering pharmacokinetically optimized GLP-1MK-801 conjugates might give rise to drugs that could outperform the current incretin-based treatments for obesity, such as semaglutide and tirzepatide

Because GLP-1 drugs frequently result in muscle mass and body fat loss, it is critical to compensate as much as possible by ingesting protein

doi: 10.1002/14651858.CD006739.pub2