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The 52-week ELEVATE UC 52 study showed 27% clinical remission in patients taking Velsipity versus 7.4% in those who were part of the placebo group at week 12, and 32.1% clinical remission compared with 6.7% at week 52

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11.7 Practical Takeaway Framework During GLP-1 therapy: Prioritise protein intake Increase micronutrient density per calorie Monitor symptoms Test selectively when risk factors are present Avoid automatic or excessive supplementation Reassess after significant weight milestones Weight loss should be metabolically effective and nutritionally sufficient

Lifestyle Shifts: Weight loss and better glycemic control often lead to more energy, improved sleep, and increased ability to participate in activities, all of which combat depressive tendencies

It is advisable to avoid self-prescribing high-dose supplements without professional guidance, as excessive intake of certain nutrients (such as fat-soluble vitamins A, D, E, and K) can be harmful