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Mazdutide (IBI362), developed by Innovent Biologics with Eli Lilly China, is an oxyntomodulin analog that has progressed through seven Phase 3 trials and gained regulatory approval in China for type 2 diabetes

Although speculative and requiring confirmation in clinical trials, the GLP-1R agonists may have beneficial effects on both sexes, dose adjustments during long treatment periods might not be needed, and the effect may persist after treatment termination

Intended strictly for controlled in vitro and in vivo research applications

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and (iv) generate chimeric mice using xenotransplantation to recapitulate human microglial biology in vivo