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According to Truveta Research presented at ISPOR 2025, side effects were the leading reason patients stopped taking GLP-1 medications, accounting for 28.2% of all discontinuations

Individuals with BED frequently experience comorbid conditions including obesity, type 2 diabetes, hypertension, and metabolic syndrome
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Following drug intervention, all three treated groups showed significant improvements in these parameters compared to untreated db/db mice [1]

A pharmacoepidemiological study analyzed electronic health records from people with both type 2 diabetes and tobacco use disorder and found that semaglutide was associated with improved smoking-related outcomes

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