using semaglutide past expiration date TrimRX What Happens if You Use
Description
Weight Loss Tirzepatide: -21.5% vs Semaglutide: -14.5% Substantial divergence with implications for long-term outcomes

Compounded semaglutide is available through licensed 503A pharmacies in California

Hims & Hers is launching a tracker of GLP-1 shortages to push back against the FDA's recent moves to end compounding copycats of the blockbuster drugs.

Obesity pharmacotherapy from the @TheAACE diabetes algorithm: GLP1/GIP and GLP1 RAs produce ~1020% weight loss with A1c reduction, while older agents like phentermine, orlistat, and naltrexone/bupropion have less efficacy and safety tradeoffs

Specifically, the study fixed 12 conserved residues from known GLP-1RAs and used ProteinMPNN to generate 10,000 novel sequences
