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These findings suggest that counterfeit semaglutide may be associated with distinct reporting patterns, potentially reflecting differences in product quality, inappropriate use, or lack of therapeutic efficacy
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The twincretin concept challenges an earlier view that GIP signalling might be counterproductive in the context of metabolic dysfunction
However, they should be used with caution in patients with advanced liver disease due to the risk of hyperkalemia and renal dysfunction [150]
Richard et al., 2014
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