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J Am Coll Cardiol 76(17):19821994 He X, Dong B, Liang W, Wu Y, Chen Y, Dong Y, He J, Liu C (2022) Ischemic risk in patients with heart failure with preserved ejection fraction: a post hoc analysis of the TOPCAT data

Clinical trials have shown groundbreaking results, with patients losing an average of 15% to 20% of their body weight within 72 weeks

Tirzepatide carries similar precautions

The STEP 4 trial showed that participants who discontinued the medication regained two-thirds of their lost weight within a year

Medical supervision, baseline labs, and regular monitoring are essential if you choose this approach
