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The primary endpoint was the 6-month healing rate, defined as a complete skin epithelialization without recurrence at 6 months, without secondary surgery (reamputation)

Checking serum creatinine (used to calculate eGFR) is recommended prior to initiating therapy with a SGLT2i

Unlike traditional water pills that may cause your body to lose potassium, spironolactone helps your body hold onto this essential mineral while still helping the kidneys remove excess water and sodium

Sustainable weight management relies on consistencytaking the same medication at the same dose week after week

The Alberta Blue Cross report notes that several notable generic medications and biosimilars under Health Canada review could provide significant cost savings for plan sponsors, though the insurer's overall view is that GLP-1 category spend will remain elevated as utilization broadens [Source: ab.bluecross.ca/plans/group/drug-pipeline-2026.php]