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doi: 10.1016/j.obpill.2024.100143 7

To date, the presence of GLP-1R in the renal vasculature has been confirmed but not in the tubules ( Oxidative Stress/Inflammation GLP-1RAs have been shown to prevent renal oxidative stress by inhibiting nicotinamide adenine dinucleotide phosphate (NADPH) oxidase through the activation of PKA and the production of cyclic adenosine monophosphate (cAMP)

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Its value is summed up by Mojsov who called it a tour de force

Digestive Changes: Diarrhea and constipation are common
