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Frequently Asked Questions Do I have to be obese to start semaglutide with PlexusDx
And, of course, avoid injecting directly into the muscle or vein Choosing the Best Place to Inject Semaglutide While the efficacy of your semaglutide injection site does matter, there is no clinically significant difference in absorption between the upper arm, thigh, and abdomen
In findings from the STEP TEENS phase 3a trial, adolescents aged 12 to 17 years with obesity or overweight and at least one weight-related coexisting condition were randomly assigned 2:1 to receive semaglutide 2.4 mg (Wegovy, Novo Nordisk) or placebo for 68 weeks

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Abbreviations CVD: Cardiovascular disease T2D: Type 2 diabetes CV: Cardiovascular HF: Heart failure GLP-1RA: Glucagon-like peptide 1 receptor agonist SGLT-2: Sodium-glucose cotransporter 2 MACE: Major cardiovascular events MI: Myocardial infarction ADA: American Diabetes Association HFrEF: Heart failure with reduced ejection fraction HFpEF: Heart failure with preserved ejection fraction FDA: Food and Drug Administration NHANES: National Health and Nutrition Examination Survey CKD: Chronic kidney disease References Grundy SM, Benjamin IJ, Burke GL, et al