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Likewise, our in vivo study demonstrated that Ach-induced endothelium-dependent vasodilation was impaired in HFD-fed ApoE / mice

Maridebart cafraglutide (known as MariTide) was a candidate to demonstrate significant efficacy in a once-monthly dosage regimen, with an average weight loss of 17% in patients at 52 weeks, with no plateau in weight loss

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The concept of incretin effect was first proposed by Creutzfeldt in the 1970s (1, 2), based on the early observations that insulin secretion was two to three times higher after oral glucose intake than that after an isocaloric intravenous glucose administration (35)

doi: 10.1111/obr.12839 [DOI] [PubMed] [Google Scholar] 97