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a definitive upper safe intake in grams per day is not established
however, daily high-sugar intake can slow or stall weight loss by adding excess calories and triggering compensatory hunger signals
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In the trial, 152 participants with an average BMI of over 38 well above the threshold for obesity got a weekly dose of semaglutide, which is injected under the skin somewhere with fat deposits, such as the stomach area or thigh and 152 others got a weekly placebo injection
After a low-calorie diet-induced weight loss of 13.1 kg for the overall cohort, the placebo group regained weight, the exercise and liraglutide groups maintained weight loss, and the combination group lost additional weight (Figure 1A)
