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The naltrexone component specifically targets the hedonic aspects of eating, making high-calorie foods less rewarding and easier to resist

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doi: 10.1016/j.npep.2018.07.003 76 BrauerRWeiLMaTAthaudaDGirgesCVijiaratnamNet al

While many states do allow an MA to hand someone a dose or inject someone, often the states require that a licensed individual draw up or verify dosage before handing it off to the MA

Sisley and colleagues used mouse genetics to inactivate the Glp1r in the mouse brain, demonstrating that the acute anorectic and chronic weight lossinducing pharmacological actions of GLP-1RA required GLP-1R expression in the central nervous system (10)