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Description
PMID 27917122
Research in earlier phases or small trials include evaluation of GLP-1s for cystic fibrosis-related diabetes, polycystic ovarian syndrome (PCOS), chronic obstructive pulmonary disease (COPD), Prader-Willi syndrome (PWS), asthma, substance or alcohol use disorder, and as add-on to insulin for type 1 diabetes (T1DM)
Val Woodring asked: How can someone tell whether a poor response to a GLP-1 is more likely related to perimenopause or chronic stress (assuming other medical conditions have been ruled out)

Tirzepatide is a dual agonist that activates both GLP-1 and GIP receptors

iGL cells were exposed to different mediums: iGL cells culture medium (Cell only), iGL culture medium supplemented with synthetic Exe4 peptide (Exe4 solution) and with scExe4 peptide secreted from Hepa1-6 and HeG2 cells transfected with the scExe4 expression plasmid (scExe4_Hepa1-6 and scExe4_HepG2, respectively)