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Sodium glucose cotransporter-2 inhibition in heart failure: potential mechanisms, clinical applications, and summary of clinical trials

However, the relationship between BMI and response to biologic therapies is not uniformly consistent across studies

Many patients tolerate the 2.5 mg starter dose fine, then run into severe GI side effects (nausea, vomiting, constipation) at the 5 mg or 7.5 mg step

They can also help you practice until you feel confident about giving your insulin dose

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