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This is one of the most practical questions and the answer depends entirely on your dose level

doi: 10.1136/postgradmedj-2013-131994, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 4.Zouboulis CC, Del Marmol V, Mrowietz U, Prens EP, Tzellos T, Jemec GB

If patients do not tolerate the 2.4 mg once-weekly maintenance dosage, the maintenance dosage may be reduced to 1.7 mg once weekly

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