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Source: Segal SHAPE, Segals data warehouse, 2018 to 2022 Even though many plans currently do not cover weight-loss medications, these plans are still seeing the effect that the GLP-1 medication class is having on their diabetic plan spend
In the ELIXA and the EXSCEL trials, GLP-1RAs (once daily lixisenatide and once weekly exenatide, respectively) didnt provide benefit in MACE reduction compared to placebo, but were non-inferior to placebo for the primary composite outcome of MACE
You still need one more 10mg vial plus some padding
Most people begin noticing reduced appetite within the first one to two weeks of starting tirzepatide
The best option really depends on your health profile, your budget, your daily routine, and what feels sustainable long term
