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supporting the system internally When you support your bodys natural processes: signaling pathways remain connected the microbiome continues to adapt and improve digestion becomes more consistent over time This approach focuses on resilience, not reliance

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5 Obesity portfolio goes beyond GLP-1 AstraZeneca is building optionality: AZD6234 (long-acting amylin) Phase 2 readout H1 2026 AZD6234 + AZD9550 (GLP-1/glucagon combo) Phase 2 readout H2 2026 $1.2B upfront to CSPC Pharmaceutical Group for ex-China rights to eight programs, led by SYH2082, a once-monthly GLP-1R/GIPR agonist My takeaway Withholding data is risky but moving into Phase 3 is louder than any slide