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In a study by Zhang et al., activation of GLP-1R was shown to mitigate novel-object recognition memory dysfunction in neuropathic pain model mice by modulating the hippocampal AMPK/NF-B signaling pathway [69] (Fig
[DOI] [PubMed] [Google Scholar] 148.Rubino D., Abrahamsson N., Davies M., Hesse D., Greenway F.L., Jensen C., Lingvay I., Mosenzon O., Rosenstock J., Rubio M.A., et al

IBMX and FSK (I5879 and F6886, MilliporeSigma) (10 M each) and 70 mM KCl were used as positive controls

However, this change was not conserved in female WT or GLPDRKO mice (Supplementary Fig
