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Nikolaos Zacharias, a vascular surgeon at Harvard-affiliated Massachusetts General Hospital

Its ability to reduce weight significantly and improve metabolic health makes it a breakthrough therapy

This is where two powerful tools emerge: weight loss medications and bariatric surgery

1 Should retatrutide affect energy expenditure in humans, it could not only help to explain weight reduction but also might influence retatrutide's effects on appetiterelated constructs

Phase 2 trials (Jastreboff et al., NEJM, 2023) have shown it to be highly effective for weight reduction in adults with obesity
