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At the same time, payer policies often require discontinuation of GLP-1 therapy when a patients BMI drops below a set threshold, inadvertently triggering a frustrating cycle of weight loss and regainthe so-called yo-yo effect. This not only impacts ongoing adherence and persistence but also undermines the long-term cost-effectiveness of these therapies for healthcare systems

While most of the recent fanfare has been related to their ro...
Activation of microglia in the trigeminal nucleus caudalis (TNC) contributes to this progression

And according to new research from the U.S

There is currently no strong evidence that GLP-1 receptor agonists directly cause thrombosis or blood clots
