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This effect is primarily mediated by two incretin hormones, namely glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP)

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Insulin icodec is an insulin form with a C20 fatty diacid albumin binder and short PEG-like linker + ?-Glu linker (see Fig

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Beneficial effects of once-daily lixisenatide on overall and postprandial glycemic levels without significant excess of hypoglycemia in Type 2 diabetes inadequately controlled on a sulfonylurea with or without metformin (GetGoal-S) J