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Description
This can create a cascade of issues over time

Nausea and vomiting, common side effects of GLP-1 therapy, can lead to volume depletion, further straining kidney function when paired with medications that inhibit the renin-angiotensin system (RAAS)

It is approved for type 2 diabetes but is often used off-label for weight loss

Oral formulations may have more direct effects on the upper GI microbiome, making probiotics that colonize the upper intestinal tract (like L

10.1093/toxsci/kfx018 291
